Clomipramine is a tricyclic antidepressant, used to treat a range of psychiactric ailments and, less commonly, as a pain-killer. It is more commonly known by the brand-name Anafranil.

The treatment is exceptionally effective at treating Obsessive Compulsive Disorder (OCD) compared to other medications in its class; it is even used for this purpose in veterinary medicine.

Many patients notice small improvements within days of starting treatment, but it may take several weeks to experience the full benefits.

A Long-Term Solution

Most of the conditions treated with clomipramine require relatively long-term treatment:

• Obsessive compulsive disorder
• Anxiety
• Depression
• Premature ejaculation
• Phobias
• Pain
• Tics
• Nail-biting and hair-pulling syndrome
• Severe pre-menstrual syndrome (PMS)

Like all antidepressants, clomipramine has the potential to produce serious side effects. The risk is small, however, if the medication is taken properly:

• Treatment should begin gradually, starting at low doses of 10 to 25 mg and increasing slowly.
• Doses should not exceed 250 mg per day for adults, or 200 mg for younger patients.
• When starting treatment, doses may be split into two or three smaller doses each day, and taken with food; when the body has adjusted to treatment, doses may be taken once daily and food is optional.
• Single, large doses are often taken in the evening as the medication may cause drowsiness, lightheadedness, and other symptoms that make it difficult to perform even routine tasks.

With regard to treating pain, premature ejaculation and pre-menstrual syndrome, the medication is often used as-needed. However, some individuals have poor results when it's taken sporadically, but find the medication quite effective as a preventative measure when taken daily on a longer-term basis. Given its potentially serious side effects, it's advisable to buy clomimpramine for these purposes only when other treatments have proven insufficient.

Before Starting Treatment

Patients of 24 years of age or younger are at particular risk of certain side effects. Though still rare, be alert for:

• Worsening depression
• Severe mood swings
• Suicidal thoughts or behavior
• Unreasonable anger or hostility
• Impulsive actions
• Other personality changes

If the above symptoms are noticed, dosage strength may be adjusted. If severe, alternate therapies may need to be explored, rather than continuing to buy clomipramine. Symptoms may develop at any time during the course of treatment.

Patients with certain preexisting conditions are also at greater risk of severe adverse reactions, particularly those with:

• History of drug or alcohol abuse
• History of mental illness or suicidal thoughts
• Any issues with the heart, lungs, liver, kidneys or thyroid

Always check with a doctor or pharmacist before mixing clomipramine with other medications; doing so may reduce effectiveness or exacerbate side effects.

Side effects are rare, and most are mild and transient. Some patients do experience more serious reactions though, which warrant medical attention:

• Very high fever
• Difficulty speaking
• Changes in heart rhythm
• Difficulty paying attention
• Memory loss
• Seizures or uncontrolled movements
• Confusion or disorientation
• Hallucinations or delusions
• Persistent fatigue or drowsiness
• Jaundice
• Personality changes

Side effects will almost always reverse when treatment is lowered or stopped altogether. If side effects are severe, speak with a doctor about alternative therapies -- there are many other treatment options out there worth exploring if clomipramine doesn't work out.

Of course, the risk of side effects are increased if the medication is used improperly. If following doctor instructions, treatment will most likely be trouble-free.

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Some localities may require a prescription to possess or buy clomipramine; clients are responsible for compliance with such laws.